Title : Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease.

Pub. Date : 2009 Nov 26

PMID : 19856923






2 Functional Relationships(s)
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1 At submicromolar concentration, they inhibit AChE and butyrylcholinesterase (BuChE) of human origin, displace the binding of propidium iodide from the PAS of AChE, and could thus inhibit Abeta aggregation promoted by AChE. Propidium acetylcholinesterase (Cartwright blood group) Homo sapiens
2 At submicromolar concentration, they inhibit AChE and butyrylcholinesterase (BuChE) of human origin, displace the binding of propidium iodide from the PAS of AChE, and could thus inhibit Abeta aggregation promoted by AChE. Propidium acetylcholinesterase (Cartwright blood group) Homo sapiens