Pub. Date : 2009 Dec 25
PMID : 19850937
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Zinc protoporphyrin regulates cyclin D1 expression independent of heme oxygenase inhibition. | zinc protoporphyrin | cyclin D1 | Mus musculus |
| 2 | Additionally, ZnPP inhibited CCND1 promoter activity through an Sp1 and Egr1 overlapping binding site (S/E). | zinc protoporphyrin | cyclin D1 | Mus musculus |
| 3 | Furthermore, administration of ZnPP significantly inhibited cyclin D1 expression and progression of a B-cell leukemia/lymphoma 1 tumor in mice by preferentially targeting tumor cells. | zinc protoporphyrin | cyclin D1 | Mus musculus |
| 4 | These observations show HO independent effects of ZnPP on cyclin D1 expression and tumorigenesis. | zinc protoporphyrin | cyclin D1 | Mus musculus |