Title : Stimulation by epidermal growth factor of inositol phosphate production in plasma membranes from A431 cells.

Pub. Date : 1991 Jan 3

PMID : 1984783






3 Functional Relationships(s)
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1 They displayed a significant phospholipase (PLC) activity against phosphoinositides, which was stimulated by guanosine 5"-O-(3-thiotriphosphate) (GTP gamma S), epidermal growth factor (EGF) and fetal calf serum (FCS) (24%, 11% and 97% over controls, respectively). Phosphatidylinositols epidermal growth factor Homo sapiens
2 They displayed a significant phospholipase (PLC) activity against phosphoinositides, which was stimulated by guanosine 5"-O-(3-thiotriphosphate) (GTP gamma S), epidermal growth factor (EGF) and fetal calf serum (FCS) (24%, 11% and 97% over controls, respectively). Phosphatidylinositols epidermal growth factor Homo sapiens
3 It is concluded that EGF might stimulate hydrolysis of phosphoinositides by PLC through complex interactions between plasma membrane and cytosolic factors which still remain to be identified. Phosphatidylinositols epidermal growth factor Homo sapiens