Title : Hypoxia selectively inhibits KCNA5 channels in pulmonary artery smooth muscle cells.

Pub. Date : 2009 Oct

PMID : 19845612






3 Functional Relationships(s)
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1 However, acute hypoxia only reduced Kv currents in KCNA5-transfected PASMC. pasmc potassium voltage-gated channel subfamily A member 5 Homo sapiens
2 These results provide compelling evidence that Kv1.5 is an important hypoxia-sensitive Kv channel in PASMC, contributing to regulation of membrane potential and intracellular Ca2+ homeostasis during hypoxia. pasmc potassium voltage-gated channel subfamily A member 5 Homo sapiens
3 This hypoxia-sensitive mechanism essential for inhibiting Kv1.5 channel activity is exclusively present in PASMC. pasmc potassium voltage-gated channel subfamily A member 5 Homo sapiens