Title : Ligand-based 3D-QSAR studies of physostigmine analogues as acetylcholinesterase inhibitors.

Pub. Date : 2009 Dec

PMID : 19843075






3 Functional Relationships(s)
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1 Ligand-based 3D-QSAR studies of physostigmine analogues as acetylcholinesterase inhibitors. Physostigmine acetylcholinesterase (Cartwright blood group) Homo sapiens
2 Natural alkaloid Physostigmine is one of the most potent pseudo-irreversible inhibitor of Acetylcholinesterase. Physostigmine acetylcholinesterase (Cartwright blood group) Homo sapiens
3 Furthermore, the analysis of comparative molecular field analysis and comparative molecular similarity indices analysis contour maps within the active site of AChE were conducted in order to understand the interactions between the receptor and the Physostigmine derivatives. Physostigmine acetylcholinesterase (Cartwright blood group) Homo sapiens