Title : Widdrol induces cell cycle arrest, associated with MCM down-regulation, in human colon adenocarcinoma cells.

Pub. Date : 2010 Apr 1

PMID : 19828235






1 Functional Relationships(s)
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1 Induction of G1 arrest by widdrol was correlated with induction of Chk2, p53 phosphorylation and CDK inhibitor p21 expression as well as inhibition of cyclin E, cyclin-dependent kinase (CDK2) and retinoblastoma protein (pRB). widdrol tumor protein p53 Homo sapiens