Title : Inhibition of cAMP responsive element binding protein in striatal neurons enhances approach and avoidance responses toward morphine--and morphine withdrawal-related cues.

Pub. Date : 2009

PMID : 19826619






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Inhibition of cAMP responsive element binding protein in striatal neurons enhances approach and avoidance responses toward morphine--and morphine withdrawal-related cues. Morphine cAMP responsive element binding protein 1 Mus musculus
2 Inhibition of cAMP responsive element binding protein in striatal neurons enhances approach and avoidance responses toward morphine--and morphine withdrawal-related cues. Morphine cAMP responsive element binding protein 1 Mus musculus
3 To investigate the role of cAMP responsive element binding protein (CREB)-dependent gene expression in morphine induced behaviors, we examined bitransgenic mice expressing a dominant and strong inhibitor of the CREB family of transcription factors, A-CREB, in striatal neurons in a regulatable manner. Morphine cAMP responsive element binding protein 1 Mus musculus
4 The expression of A-CREB in the striatum enhanced both morphine-induced conditioned place preference and morphine withdrawal-induced conditioned place avoidance. Morphine cAMP responsive element binding protein 1 Mus musculus
5 The expression of A-CREB in the striatum enhanced both morphine-induced conditioned place preference and morphine withdrawal-induced conditioned place avoidance. Morphine cAMP responsive element binding protein 1 Mus musculus