Title : Carbonic anhydrase inhibitors: glycosylsulfanilamides act as subnanomolar inhibitors of the human secreted isoform VI.

Pub. Date : 2009 Dec

PMID : 19824891






1 Functional Relationships(s)
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1 Many of these sulfonamides were also selective inhibitors for their interaction with CA VI over the physiologically dominant and ubiquitous isoform CA II, with selectivity ratios of 4.11-35.93 for inhibiting the secreted over the cytosolic isozyme. Sulfonamides carbonic anhydrase 2 Homo sapiens