Title : The ability of cytochrome P450 2D isoforms to synthesize dopamine in the brain: An in vitro study.

Pub. Date : 2010 Jan 25

PMID : 19818757






2 Functional Relationships(s)
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1 The reaction was inhibited by the CYP2D inhibitor quinine and by anti-CYP2D4 antibodies, which suggests that CYP2D4 is the isoform governing tyramine hydroxylation to dopamine in the rat brain. Tyramine cytochrome P450, family 2, subfamily d, polypeptide 4 Rattus norvegicus
2 The reaction was inhibited by the CYP2D inhibitor quinine and by anti-CYP2D4 antibodies, which suggests that CYP2D4 is the isoform governing tyramine hydroxylation to dopamine in the rat brain. Tyramine cytochrome P450, family 2, subfamily d, polypeptide 4 Rattus norvegicus