Title : Cytoplasmic ACK1 interaction with multiple receptor tyrosine kinases is mediated by Grb2: an analysis of ACK1 effects on Axl signaling.

Pub. Date : 2009 Dec 11

PMID : 19815557






1 Functional Relationships(s)
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1 Unlike the interaction between MIG6 and EGFR, our data suggest that these receptor tyrosine kinases require the adaptor protein Grb2 for efficient binding, which interacts with highly conserved proline-rich regions that are conserved between ACK1 and MIG6. Proline growth factor receptor bound protein 2 Homo sapiens