Title : Differential metabolic responses to pluronic in MDR and non-MDR cells: a novel pathway for chemosensitization of drug resistant cancers.

Pub. Date : 2010 Feb 25

PMID : 19815037






2 Functional Relationships(s)
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1 Furthermore, inhibition of Pgp functional activity also abolishes the effects of Pluronic on intracellular ATP levels in MDR cells suggesting that Pgp contributes to increased responsiveness of molecular "targets" of Pluronic in the mitochondria of MDR cells. Adenosine Triphosphate ATP binding cassette subfamily B member 1 Homo sapiens
2 Furthermore, inhibition of Pgp functional activity also abolishes the effects of Pluronic on intracellular ATP levels in MDR cells suggesting that Pgp contributes to increased responsiveness of molecular "targets" of Pluronic in the mitochondria of MDR cells. Adenosine Triphosphate ATP binding cassette subfamily B member 1 Homo sapiens