Title : Influence of genetic variation in CYP3A4 and ABCB1 on dose decrease or switching during simvastatin and atorvastatin therapy.

Pub. Date : 2010 Jan

PMID : 19802823






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We studied whether the polymorphism CYP3A4*1B and the polymorphisms C1236T, G2677A/T and C3435T in the ABCB1 gene were associated with a decrease of the prescribed dose or a switch to another cholesterol lowering drug during simvastatin and atorvastatin therapy. Cholesterol ATP binding cassette subfamily B member 1 Homo sapiens