Title : Chlorpyrifos induces delayed cytotoxicity after withdrawal in primary hippocampal neurons through extracellular signal-regulated kinase inhibition.

Pub. Date : 2009 Oct

PMID : 19801823






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Carbacol and nerve growth factor (NGF), which are ERK1/2 activators, protected the neurons after CPF withdrawal, while atropine and PD98059, which are ERK1/2 inhibitors, exacerbated the cytotoxicity, indicating the involvement of inhibition of ERK1/2 phosphorylation in CPF-induced delayed cytotoxicity. Carbachol mitogen activated protein kinase 3 Rattus norvegicus