Title : Pyridine analogues of nimesulide: design, synthesis, and in vitro and in vivo pharmacological evaluation as promising cyclooxygenase 1 and 2 inhibitors.

Pub. Date : 2009 Oct 8

PMID : 19791801






1 Functional Relationships(s)
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1 In the present study, we report the synthesis and the pharmacological evaluation of pyridine analogues of nimesulide, a COX-2 preferential inhibitor. nimesulide mitochondrially encoded cytochrome c oxidase II Homo sapiens