Title : Predicting gemcitabine transport and toxicity in human pancreatic cancer cell lines with the positron emission tomography tracer 3'-deoxy-3'-fluorothymidine.

Pub. Date : 2010 Feb 15

PMID : 19788890






1 Functional Relationships(s)
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1 Capan-2 cells displayed the lowest levels of (1) extracellular nitrobenzylmercaptopurine ribonucleoside (NBMPR) binding, which represents cell-surface hENT1, (2) FLT and gemcitabine uptake during short (1-45s) and prolonged (1h) periods, and (3) gemcitabine sensitivity. Nitrobenzylmercaptopurine Ribonucleoside solute carrier family 29 member 1 (Augustine blood group) Homo sapiens