Title : Partial down-regulation of protein kinase C reverses the growth inhibitory effect of phorbol esters on HepG2 cells.

Pub. Date : 1990 Nov

PMID : 1978839






1 Functional Relationships(s)
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1 Northern blot analysis of a number of transcripts showed that the steady-state levels of c-myc and transforming growth factor beta 1 (TGF-beta 1) messages increased only after 3 h of phorbol ester treatment and returned to normal levels after 24 h. C-fos, albumin, and alphafetoprotein messages were not affected, suggesting the differentiation state of the cells was not altered. Phorbol Esters MYC proto-oncogene, bHLH transcription factor Homo sapiens