Title : Conjugated polyelectrolyte-sensitized fluorescent detection of thrombin in blood serum using aptamer-immobilized silica nanoparticles as the platform.

Pub. Date : 2009 Nov 3

PMID : 19785411






1 Functional Relationships(s)
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1 As a result of specific protein/aptamer interaction, the presence of thrombin induces the primary aptamer-functionalized NPs to form a sandwich structure with fluorescein-labeled secondary aptamer and results in fluorescent NPs. Fluorescein coagulation factor II, thrombin Homo sapiens