Title : Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death.

Pub. Date : 2009 Oct

PMID : 19783996






2 Functional Relationships(s)
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1 In cell lines, upon cisplatin treatment, c-Abl phosphorylates TAp63 on specific tyrosine residues. Cisplatin c-abl oncogene 1, non-receptor tyrosine kinase Mus musculus
2 Treatment with the c-Abl kinase inhibitor imatinib counteracts these cisplatin-induced effects. Cisplatin c-abl oncogene 1, non-receptor tyrosine kinase Mus musculus