Title : Fine tuning T lymphocytes: a role for the lipid phosphatase SHIP-1.

Pub. Date : 2010 Mar

PMID : 19782768






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 One level of control involves the Src homology 2 domain-containing inositol-5-phosphatase-1 (SHIP-1) that modulates phosphoinositide 3-kinase signaling by degrading the key signaling lipid PI(3,4,5)P(3) to PI(3,4)P(2), but also serves as a key scaffolding molecule in the formation of multi-protein complexes. pi(3,4)p inositol polyphosphate-5-phosphatase D Homo sapiens
2 One level of control involves the Src homology 2 domain-containing inositol-5-phosphatase-1 (SHIP-1) that modulates phosphoinositide 3-kinase signaling by degrading the key signaling lipid PI(3,4,5)P(3) to PI(3,4)P(2), but also serves as a key scaffolding molecule in the formation of multi-protein complexes. pi(3,4)p inositol polyphosphate-5-phosphatase D Homo sapiens