Title : Structure and function of the molecular chaperone Hsp104 from yeast.

Pub. Date : 2010 Mar

PMID : 19768774






3 Functional Relationships(s)
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1 In yeast models of Huntington"s disease, Hsp104 is required for the aggregation and toxicity of polyglutamine (polyQ), but the expression of Hsp104 in cellular and animal models of Huntington"s and Parkinson"s disease protects against polyQ and alpha-synuclein toxicity. polyglutamine chaperone ATPase HSP104 Saccharomyces cerevisiae S288C
2 In yeast models of Huntington"s disease, Hsp104 is required for the aggregation and toxicity of polyglutamine (polyQ), but the expression of Hsp104 in cellular and animal models of Huntington"s and Parkinson"s disease protects against polyQ and alpha-synuclein toxicity. polyglutamine chaperone ATPase HSP104 Saccharomyces cerevisiae S288C
3 In yeast models of Huntington"s disease, Hsp104 is required for the aggregation and toxicity of polyglutamine (polyQ), but the expression of Hsp104 in cellular and animal models of Huntington"s and Parkinson"s disease protects against polyQ and alpha-synuclein toxicity. polyglutamine chaperone ATPase HSP104 Saccharomyces cerevisiae S288C