Title : Targeted disruption of stat3 reveals a major role for follicular stem cells in skin tumor initiation.

Pub. Date : 2009 Oct 1

PMID : 19738054






1 Functional Relationships(s)
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1 Targeted disruption of Stat3 in bulge region KSCs at the time of initiation also dramatically reduced the number of skin tumors (by approximately 80%) produced following promotion with the phorbol ester 12-O-tetradecanoylphorbol-13-acetate. Tetradecanoylphorbol Acetate signal transducer and activator of transcription 3 Mus musculus