Title : A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure.

Pub. Date : 2009 Sep 4

PMID : 19737523






1 Functional Relationships(s)
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1 We show here that brainstem-derived serotonin (BDS) favors bone mass accrual following its binding to Htr2c receptors on ventromedial hypothalamic neurons and appetite via Htr1a and 2b receptors on arcuate neurons. Serotonin 5-hydroxytryptamine receptor 2C Homo sapiens