Title : Expression of mdr1 and mdr3 multidrug-resistance genes in human acute and chronic leukemias and association with stimulation of drug accumulation by cyclosporine.

Pub. Date : 1990 Jul 4

PMID : 1972761






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In vitro drug uptake studies by on-line flow cytometry showed that in leukemia cells expressing either mdr1 or mdr3, the steady-state accumulation of daunorubicin could be significantly increased by addition of cyclosporine and, to a lesser extent, by verapamil. Daunorubicin ATP binding cassette subfamily B member 4 Homo sapiens