Title : Neuromodulation: associative and nonlinear adaptation.

Pub. Date : 1990 May

PMID : 1972647






3 Functional Relationships(s)
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1 A neuromodulatory interaction that has been linked to memory function and which has been the subject of biochemical inquiry is the interaction between the catecholamine, norepinephrine (NE) and the neuropeptide, vasopressin (AVP). Norepinephrine arginine vasopressin Homo sapiens
2 Studies described in this report show that vasopressin acts to potentiate norepinephrine (NE)-induced cyclic adenosine monophosphate (cAMP) accumulation in the hippocampus by a calcium-dependent mechanism. Norepinephrine arginine vasopressin Homo sapiens
3 By using vasopressin potentiation of noradrenalin-induced cAMP formation as a model system, I have applied the theoretical framework of associative learning and memory to test the hypothesis that neuromodulation can serve as a biochemical analog of associative cognitive events. Norepinephrine arginine vasopressin Homo sapiens