Pub. Date : 2009 Aug 31
PMID : 19714314
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4(+) T cells. | Tacrolimus | CD4 molecule | Homo sapiens |
| 2 | However, the exact pharmacological effects of tacrolimus on CD4(+) T cells have yet to be elucidated. | Tacrolimus | CD4 molecule | Homo sapiens |
| 3 | This study investigated the effects of tacrolimus on CD4(+) T cell subsets. | Tacrolimus | CD4 molecule | Homo sapiens |
| 4 | In the case of conventional CD4(+) T cells (Tconv cells), tacrolimus inhibited T cell receptor stimulation-induced cell division. | Tacrolimus | CD4 molecule | Homo sapiens |
| 5 | In contrast, the cell division of regulatory CD4(+) T cells (Treg cells) was even promoted in the presence of tacrolimus, especially in humans. | Tacrolimus | CD4 molecule | Homo sapiens |