Pub. Date : 2010 Mar 1
PMID : 19713035
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The present study evaluated the effects of interfering with the TGF-beta signaling pathway on the radiosensitivity of selected human tumor cell lines using the plant-derived alkaloid, halofuginone. | halofuginone | transforming growth factor beta 1 | Homo sapiens |
| 2 | Halofuginone treatment inhibited cell growth, halted cell cycle progression, decreased radiation-induced DNA damage repair, and decreased TGF-beta receptor II protein levels, leading to increased cellular radiosensitization. | halofuginone | transforming growth factor beta 1 | Homo sapiens |