Title : Metabolism of loratadine and further characterization of its in vitro metabolites.

Pub. Date : 2009 Aug

PMID : 19702548






1 Functional Relationships(s)
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1 The present study demonstrated that in addition to CYP3A4 and CYP2D6, the metabolism of loratadine is also catalyzed by CYP1A1, CYP2C19, and to a lesser extent by CYP1A2, CYP2B6, CYP2C8, CYP2C9 and CYP3A5. Loratadine cytochrome P450 family 3 subfamily A member 5 Homo sapiens