Title : Dermatan sulfate epimerase 1-deficient mice have reduced content and changed distribution of iduronic acids in dermatan sulfate and an altered collagen structure in skin.

Pub. Date : 2009 Oct

PMID : 19687302






5 Functional Relationships(s)
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1 Dermatan sulfate epimerase 1-deficient mice have reduced content and changed distribution of iduronic acids in dermatan sulfate and an altered collagen structure in skin. Dermatan Sulfate dermatan sulfate epimerase Mus musculus
2 Dermatan sulfate epimerase 1 (DS-epi1) and DS-epi2 convert glucuronic acid to iduronic acid in chondroitin/dermatan sulfate biosynthesis. Dermatan Sulfate dermatan sulfate epimerase Mus musculus
3 Dermatan sulfate epimerase 1 (DS-epi1) and DS-epi2 convert glucuronic acid to iduronic acid in chondroitin/dermatan sulfate biosynthesis. Dermatan Sulfate dermatan sulfate epimerase Mus musculus
4 The lack of DS-epi1 affects the chondroitin/dermatan sulfate in many proteoglycans, and the consequences for skin collagen structure were initially analyzed. Dermatan Sulfate dermatan sulfate epimerase Mus musculus
5 The altered chondroitin/dermatan sulfate chains carried by decorin in skin are likely to affect collagen fibril formation and reduce the tensile strength of DS-epi1-null skin. Dermatan Sulfate dermatan sulfate epimerase Mus musculus