Title : Examination of Zolpidem effects on AhR- and PXR-dependent expression of drug-metabolizing cytochromes P450 in primary cultures of human hepatocytes.

Pub. Date : 2009 Dec 1

PMID : 19686824






1 Functional Relationships(s)
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1 The levels of CYP1A1, CYP1A2, CY2C9 and CYP3A4 mRNAs were not altered by Zolpidem, whereas model inducers dioxin and rifampicin significantly induced CYP1A and CYP2/3 gene expression, respectively. Rifampin cytochrome P450 family 1 subfamily A member 2 Homo sapiens