Pub. Date : 2009 Nov
PMID : 19681813
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tacrolimus, a cornerstone immunosuppressant, is widely available as a twice-daily formulation (Tacrolimus BID). | Tacrolimus | BH3 interacting domain death agonist | Homo sapiens |
| 2 | Tacrolimus, a cornerstone immunosuppressant, is widely available as a twice-daily formulation (Tacrolimus BID). | Tacrolimus | BH3 interacting domain death agonist | Homo sapiens |
| 3 | This study compared the pharmacokinetics (PK) of tacrolimus in de novo kidney transplant patients treated with Tacrolimus QD or Tacrolimus BID. | Tacrolimus | BH3 interacting domain death agonist | Homo sapiens |
| 4 | Mean AUC(0-24) of tacrolimus on day 1 was approximately 30% lower for Tacrolimus QD than Tacrolimus BID (232 and 361 ng.h/mL, respectively), but was comparable by day 4. | Tacrolimus | BH3 interacting domain death agonist | Homo sapiens |
| 5 | Tacrolimus QD can be administered once daily in the morning on the basis of the same systemic exposure and therapeutic drug monitoring concept as Tacrolimus BID. | Tacrolimus | BH3 interacting domain death agonist | Homo sapiens |