Title : Curcumin blocks prostaglandin E2 biosynthesis through direct inhibition of the microsomal prostaglandin E2 synthase-1.

Pub. Date : 2009 Aug

PMID : 19671757






1 Functional Relationships(s)
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1 Curcumin, a polyphenolic beta-diketone from tumeric with anti-carcinogenic and anti-inflammatory activities, was shown to suppress PGE(2) formation and to block the expression of COX-2 and of microsomal PGE(2) synthase-1. Curcumin mitochondrially encoded cytochrome c oxidase II Homo sapiens