Pub. Date : 2009 Aug 18
PMID : 19666531
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Adseverin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins. | Calcium | gelsolin | Homo sapiens |
| 2 | This structure is highly similar to that of the activated form of the C-terminal half of gelsolin (G4-G6), both in arrangement of domains and in the 3 bound calcium ions. | Calcium | gelsolin | Homo sapiens |
| 3 | A model of calcium-free adseverin, constructed from the structure of gelsolin, predicts that in the absence of a gelsolin-like C-terminal extension the interaction between A2 and A6 provides the steric inhibition to prevent interaction with F-actin. | Calcium | gelsolin | Homo sapiens |