Title : Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways.

Pub. Date : 2009 Oct 9

PMID : 19666465






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways. sapropterin nitric oxide synthase 3 Homo sapiens
2 Tetrahyrobiopterin (BH4) is a required cofactor for the synthesis of nitric oxide by endothelial nitric-oxide synthase (eNOS), and BH4 bioavailability within the endothelium is a critical factor in regulating the balance between NO and superoxide production by eNOS (eNOS coupling). sapropterin nitric oxide synthase 3 Homo sapiens