Title : Overexpression of Cu/Zn-superoxide dismutase and/or catalase accelerates benzo(a)pyrene detoxification by upregulation of the aryl hydrocarbon receptor in mouse endothelial cells.

Pub. Date : 2009 Oct 15

PMID : 19666105






1 Functional Relationships(s)
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1 In addition, the BaP-induced CYP1A1 and 1B1 protein levels and BaP-elevated glutathione S-transferase (GST) activity were significantly higher in these transgenic cells, in parallel with elevated GSTp1, CYP1A1, and CYP1B1 mRNA levels, compared to wild-type MAECs. Benzo(a)pyrene cytochrome P450, family 1, subfamily b, polypeptide 1 Mus musculus