Pub. Date : 2009 Oct 9
PMID : 19664603
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Lycopene inhibits PDGF-BB-induced retinal pigment epithelial cell migration by suppression of PI3K/Akt and MAPK pathways. | Lycopene | AKT serine/threonine kinase 1 | Homo sapiens |
2 | Lycopene shows no effect on ARPE19 cell adhesion and is found to inhibit PDGF-BB-induced tyrosine phosphorylation and the underlying signaling pathways of PI3K, Akt, ERK and p38 activation. | Lycopene | AKT serine/threonine kinase 1 | Homo sapiens |
3 | Taken together, our results demonstrate that lycopene inhibits PDGF-BB-induced ARPE19 cell migration through inhibition of PI3K/Akt, ERK and p38 activation. | Lycopene | AKT serine/threonine kinase 1 | Homo sapiens |