Title : The interaction between thymine DNA glycosylase and nuclear receptor coactivator 3 is required for the transcriptional activation of nuclear hormone receptors.

Pub. Date : 2010 Jan

PMID : 19652917






1 Functional Relationships(s)
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1 Mutation of the two aspartic acids (aa 294 and 297) into two alanines in TDG significantly affected the interaction and subsequent transcriptional activation of several steroid hormone receptors including, estrogen-, androgen- and progesterone- receptors in Huh7 cells. Aspartic Acid thymine DNA glycosylase Homo sapiens