Title : Duodenal acidity "sensing" but not epithelial HCO3- supply is critically dependent on carbonic anhydrase II expression.

Pub. Date : 2009 Aug 4

PMID : 19622732






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here, we report the physiological role of the intracellular CAII isoform involvement in acid-, PGE(2,) and forskolin-induced murine duodenal bicarbonate secretion (DBS) in vivo. Bicarbonates carbonic anhydrase 2 Mus musculus
2 The results suggest that CA II is important for duodenocyte acidification by low luminal pH and for eliciting the acid-mediated HCO(3)(-) secretory response, but is not important in the generation of the secreted HCO(3)(-) ions. Bicarbonates carbonic anhydrase 2 Mus musculus