Title : Outcome of patients with early-stage breast cancer treated with doxorubicin-based adjuvant chemotherapy as a function of HER2 and TOP2A status.

Pub. Date : 2009 Aug 20

PMID : 19620488






1 Functional Relationships(s)
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1 PURPOSE: Amplification and deletion of the TOP2A gene have been reported as positive predictive markers of response to anthracycline-based therapy. Anthracyclines DNA topoisomerase II alpha Homo sapiens