Pub. Date : 2009 Jul 15
PMID : 19605690
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Removal of maternal retinoic acid by embryonic CYP26 is required for correct Nodal expression during early embryonic patterning. | Tretinoin | cytochrome P450, family 26, subfamily a, polypeptide 1 | Mus musculus |
| 2 | The abundance of retinoic acid (RA) is determined by the balance between its synthesis by retinaldehyde dehydrogenase (RALDH) and its degradation by CYP26. | Tretinoin | cytochrome P450, family 26, subfamily a, polypeptide 1 | Mus musculus |
| 3 | The abundance of retinoic acid (RA) is determined by the balance between its synthesis by retinaldehyde dehydrogenase (RALDH) and its degradation by CYP26. | Tretinoin | cytochrome P450, family 26, subfamily a, polypeptide 1 | Mus musculus |
| 4 | In particular, the dynamic expression of three CYP26 genes controls the regional level of RA within the body. | Tretinoin | cytochrome P450, family 26, subfamily a, polypeptide 1 | Mus musculus |
| 5 | These observations suggest that maternal RA must be removed by embryonic CYP26 for correct Nodal expression during embryonic patterning. | Tretinoin | cytochrome P450, family 26, subfamily a, polypeptide 1 | Mus musculus |