Pub. Date : 2009 Oct
PMID : 19597933
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Acute intrastriatal administration of quinolinic acid affects the expression of the coat protein AP-2 and its interaction with membranes. | Quinolinic Acid | transcription factor AP-2 alpha | Homo sapiens |
2 | In this study, we demonstrated that acute intrastriatal administration of quinolinic acid (QUIN), an agonist of the N-methyl-D: -aspartate receptor, induces a decrease of the coat protein AP-2 expression and affects their interaction with membranes. | Quinolinic Acid | transcription factor AP-2 alpha | Homo sapiens |
3 | In this study, we demonstrated that acute intrastriatal administration of quinolinic acid (QUIN), an agonist of the N-methyl-D: -aspartate receptor, induces a decrease of the coat protein AP-2 expression and affects their interaction with membranes. | Quinolinic Acid | transcription factor AP-2 alpha | Homo sapiens |
4 | By western blot analysis we observed that at 24 h after QUIN intrastriatal injection, alpha1 subunit of AP-2 and alpha2, at lesser extent, were reduced in the striatal membranes. | Quinolinic Acid | transcription factor AP-2 alpha | Homo sapiens |
5 | We concluded that QUIN may affect the endocytotic machinery of the striatum, by inducing changes in the AP-2 behaviour. | Quinolinic Acid | transcription factor AP-2 alpha | Homo sapiens |