Title : Shock membrane electropotential drops and limited diffusive distance of beta-amyloids in cerebral neurons are detrimental enhancement to Alzheimer's diseases.

Pub. Date : 2009 Oct 15

PMID : 19574031






1 Functional Relationships(s)
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1 Molecular physicobiochemical calculations indicated that the metallic ion binding to beta-amyloids (Abeta) may induce production of hydrogen peroxide, which triggers the Ca ion redistribution from the extracellular to the intracellular compartmentation, resulting in a transient membrane electropotential drop by at least 208.06 mV. Hydrogen Peroxide amyloid beta precursor protein Homo sapiens