Title : ATF3 plays a protective role against toxicity by N-terminal fragment of mutant huntingtin in stable PC12 cell line.

Pub. Date : 2009 Aug 25

PMID : 19559011






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Huntington"s disease is a progressive neurodegenerative disorder caused by a polyglutamine expansion near the N-terminus of huntingtin. polyglutamine huntingtin Rattus norvegicus
2 We have studied gene expression profiles by short oligo array using an inducible PC12 cell model expressing an N-terminal huntingtin fragment with expanded polyglutamine (Htt-N63-148Q). polyglutamine huntingtin Rattus norvegicus
3 We have studied gene expression profiles by short oligo array using an inducible PC12 cell model expressing an N-terminal huntingtin fragment with expanded polyglutamine (Htt-N63-148Q). polyglutamine huntingtin Rattus norvegicus