Title : Interleukin-10 promoter polymorphisms in hepatitis C patients with and without Schistosoma mansoni co-infection.

Pub. Date : 2009 Oct

PMID : 19555400






2 Functional Relationships(s)
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1 Given that interindividual variations in IL-10 production are influenced by functional polymorphisms in the IL-10 gene promoter, we determined the frequencies of common (-1082, -819 and -592) IL-10 promoter polymorphisms in chronic HCV patients with and without S. mansoni co-infection and healthy controls, and investigated their association with the degree of histological activity index (HAI) and response to interferon-ribavirin therapy. Ribavirin interleukin 10 Homo sapiens
2 Given that interindividual variations in IL-10 production are influenced by functional polymorphisms in the IL-10 gene promoter, we determined the frequencies of common (-1082, -819 and -592) IL-10 promoter polymorphisms in chronic HCV patients with and without S. mansoni co-infection and healthy controls, and investigated their association with the degree of histological activity index (HAI) and response to interferon-ribavirin therapy. Ribavirin interleukin 10 Homo sapiens