Title : Insulin mediators are the signal transduction system responsible for insulin's actions on human placental steroidogenesis.

Pub. Date : 1991 Dec

PMID : 1954880






1 Functional Relationships(s)
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1 When human cytotrophoblasts were incubated in medium supplemented with androstenedione for 24 h, treatment with IM-pH 2.0 or IM-pH 1.3 suppressed aromatase activity by 15% (P less than 0.05) and 49% (P less than 0.05), respectively, compared to insulin, which suppressed aromatase activity by 21% (P less than 0.05). Androstenedione insulin Homo sapiens