Pub. Date : 2009 Aug
PMID : 19531897
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: The P2Y(12) adenosine diphosphate (ADP) receptor blocker, clopidogrel, an essential drug for the prevention of stent thrombosis after percutaneous coronary intervention (PCI), is a prodrug that requires CYP2C19- and CYP3A4-mediating activation. | Clopidogrel | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 2 | The effect of polymorphisms of CYP2C19, CYP3A4 and P2Y(12) on the antiplatelet effect of clopidogrel in clinical patients was examined in the present study. | Clopidogrel | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |