Title : Genetic relatedness and molecular characterization of multidrug resistant Acinetobacter baumannii isolated in central Ohio, USA.

Pub. Date : 2009 Jun 17

PMID : 19531268






2 Functional Relationships(s)
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1 The presence of bla(OXA-23) in 13% (11/83) and IS(Aba1) linked bla(OXA-66) in 79.5% (66/83) of clinical isolates was associated with high level imipenem resistance. Imipenem class D beta-lactamase OXA-23 Acinetobacter baumannii
2 CONCLUSION: This study underscores the major role of carbapenem-hydrolyzing class D beta-lactamases, and in particular the acquired OXA-23, in the dissemination of imipenem-resistant A. baumannii. Imipenem class D beta-lactamase OXA-23 Acinetobacter baumannii