Title : Construction and characterization of a cell line deficient in repair of mitochondrial, but not nuclear, oxidative DNA damage.

Pub. Date : 2009

PMID : 19513679






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Knockdown of MUTYH which excises adenine opposite 8-oxoG in DNA prevents degradation of mitochondrial DNA and activation of calpain, thus suppressing the cell death induced by menadione. Adenine mutY DNA glycosylase Homo sapiens