Title : Dual activity lysophosphatidic acid receptor pan-antagonist/autotaxin inhibitor reduces breast cancer cell migration in vitro and causes tumor regression in vivo.

Pub. Date : 2009 Jul 1

PMID : 19509223






1 Functional Relationships(s)
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Protein Name
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1 The syn and anti diastereomers of BrP-LPA are pan-LPA GPCR antagonists and are also nanomolar inhibitors of the lysophospholipase D activity of autotaxin, the dominant biosynthetic source of LPA. lysophosphatidic acid ectonucleotide pyrophosphatase/phosphodiesterase 2 Mus musculus