Title : In vitro micronucleus test in HepG2 transformants expressing a series of human cytochrome P450 isoforms with chemicals requiring metabolic activation.

Pub. Date : 2009 Jun-Jul

PMID : 19501186






1 Functional Relationships(s)
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1 Among these transformants, benzo(a)pyrene-induced or cyclophosphamide-produced micronucleus (MN) frequency was markedly increased in transformants expressing CYP1A2 or CYP2C9, respectively. Benzo(a)pyrene cytochrome P450 family 1 subfamily A member 2 Homo sapiens