Title : Diferuloylmethane augments the cytotoxic effects of piplartine isolated from Piper chaba.

Pub. Date : 2009 Sep

PMID : 19501152






1 Functional Relationships(s)
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1 In PCC4 cells, piplartine inhibited the cell cycle progression by inactivating cdk2 and destabilizing cyclin D1, whereas diferuloylmethane combination inhibited the ERK1/2 and Raf-1 signaling in addition to the inhibition of cell cycle progression. Curcumin mitogen-activated protein kinase 3 Mus musculus